Caveolin 3 antibody
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- Target See all Caveolin 3 (CAV3) Antibodies
- Caveolin 3 (CAV3)
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caveolin 3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human CAV3
- Isotype
- IgG
- Top Product
- Discover our top product CAV3 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:25-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Caveolin 3 (CAV3)
- Alternative Name
- CAV3 (CAV3 Products)
- Background
- This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
- Molecular Weight
- 17 kDa
- NCBI Accession
- NP_001225
- UniProt
- P56539
- Pathways
- Carbohydrate Homeostasis, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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