The Rabbit Polyclonal anti-SIGLEC6 antibody (ABIN7238771) specifically detects SIGLEC6 in ELISA, WB and IHC.
The antibody is reactive with Human samples.
TheSIGLEC6gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.