CDK11 antibody

Catalog No. ABIN7238792

The Rabbit Polyclonal anti-CDK11 antibody has been validated for WB, ELISA and IHC. It is suitable to detect CDK11 in samples from Human and Mouse.

Quick Overview for CDK11 antibody (ABIN7238792)

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CDK11 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human CDK11A/CDK11B

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDK11

Target: CDK11 (CDK11B) (Cyclin-Dependent Kinase 11B (CDK11B))

Alternative Name: CDK11B

Background: Cyclin-dependent kinases (CDKs)are a family ofproteinkinasesfirst discovered for their role in regulating thecell cycle. They are also involved in regulatingtranscription, mRNA processing, and the differentiation of nerve cells. They are present in all knowneukaryotes, and their regulatory function in thecell cyclehas been evolutionarily conserved. CDKs are relatively small proteins, witHuman, Mouseolecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity, only the cyclin-CDK complex is an active kinase. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases.

Molecular Weight: 93 kDa

NCBI Accession: NP_277021

UniProt: B7ZVY7

Pathways: Regulation of Lipid Metabolism by PPARalpha, M Phase