OMG antibody

Catalog No. ABIN7001420

This Rabbit Polyclonal antibody specifically detects OMG in ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for OMG antibody (ABIN7001420)

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OMG antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-OMG Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human OMG

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for OMG

Target: OMG (Oligodendrocyte Myelin Glycoprotein (OMG))

Alternative Name: OMG

Background: Oligodendrocyte myelin glycoprotein (OMG, OMgp) is a glycosylphosphatidylinositol-anchored protein expressed by neurons and oligodendrocytes that influences the development of the adult central nervous system (CNS). OMG inhibits neurite outgrowth through its interaction with the Nogo receptor. This function requires its leucine-rich repeat domain, a highly-conserved region in OMG that influences cell proliferation, formation and maintenance of myelin sheaths. OMG inhibits neurite outgrowth from rat cerebellar granule and hippocampal cells, from dorsal root ganglion explants in which growth cone collapse was observed, from rat retinal ganglion neurons, and from NG108 and PC-12 cells.

NCBI Accession: NP_002535

UniProt: P23515

Pathways: Neurotrophin Signaling Pathway, Regulation of Cell Size