RNLS antibody

Catalog No. ABIN7001475

The Rabbit Polyclonal anti-RNLS antibody has been validated for WB and ELISA. It is suitable to detect RNLS in samples from Human, Mouse and Rat.

Quick Overview for RNLS antibody (ABIN7001475)

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNLS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RNLS Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human RNLS

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RNLS

Target: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Alternative Name: RNLS

Background: Renalase is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. Catalyzes the oxidation of the less abundant alpha-NAD(P)H isoform toform beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk.

Molecular Weight: 38 kDa

NCBI Accession: NP_001026879

UniProt: Q5VYX0