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CBS antibody

The Rabbit Polyclonal anti-CBS antibody has been validated for WB and ELISA. It is suitable to detect CBS in samples from Human, Mouse and Rat.
Catalog No. ABIN7240652

Quick Overview for CBS antibody (ABIN7240652)

Target

See all CBS Antibodies
CBS (Cystathionine-beta-Synthase (CBS))

Reactivity

  • 60
  • 47
  • 14
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 72
  • 11
Rabbit

Clonality

  • 65
  • 18
Polyclonal

Conjugate

  • 48
  • 6
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CBS antibody is un-conjugated

Application

  • 65
  • 33
  • 25
  • 19
  • 13
  • 13
  • 13
  • 11
  • 8
  • 8
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Characteristics

    Polyclonal Antibody

    Purification

    Affinity purification

    Immunogen

    Recombinant protein of human CBS

    Isotype

    IgG
  • Application Notes

    WB 1:200-1:1000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.2 mg/mL

    Buffer

    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    CBS (Cystathionine-beta-Synthase (CBS))

    Alternative Name

    CBS

    Background

    The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

    Molecular Weight

    61 kDa

    UniProt

    P35520
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