Sonic Hedgehog antibody
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- Target See all Sonic Hedgehog (SHH) Antibodies
- Sonic Hedgehog (SHH)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Sonic Hedgehog antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human SHH
- Isotype
- IgG
- Top Product
- Discover our top product SHH Primary Antibody
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anti-Sonic Hedgehog (SHH) (AA 21-120) antibody
SHH Reactivity: Human, Mouse, Rat, Pig WB, ELISA, IF (cc), IHC (p), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 5H4 unconjugated
anti-Sonic Hedgehog (SHH) (C-Term) antibodyVerified SHH Reactivity: Human, Mouse WB, ELISA, IF, FACS Host: Goat Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (N-Term) antibodySHH Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Goat, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 26-161) antibodySHH Reactivity: Human, Mouse, Monkey WB, IHC, ELISA, FACS Host: Mouse Monoclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Sonic Hedgehog (SHH) (AA 36-193) antibodySHH Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal D6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 58-91), (N-Term) antibodySHH Reactivity: Human, Mouse, Rat WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB52387 unconjugated
anti-Sonic Hedgehog (SHH) (AA 24-197) antibodySHH Reactivity: Human, Rat, Dog, Monkey WB, IF Host: Mouse Monoclonal 10H6 unconjugated
anti-Sonic Hedgehog (SHH) (AA 237-399) antibodySHH Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- IHC 1:50-1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.8 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Sonic Hedgehog (SHH)
- Alternative Name
- SHH (SHH Products)
- Background
- This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities.
- NCBI Accession
- NP_000184
- UniProt
- Q15465
- Pathways
- Hedgehog Signaling, Dopaminergic Neurogenesis, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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