RRAD antibody

Catalog No. ABIN7242650

This anti-RRAD antibody is a Rabbit Polyclonal antibody detecting RRAD in IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for RRAD antibody (ABIN7242650)

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRAD antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-RRAD Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human RRAD

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for RRAD

Target: RRAD (Ras-Related Associated with Diabetes (RRAD))

Alternative Name: RRAD

Background: The protein may be important in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca2+ currents. As regulator of voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane. Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway and phosphorylation and activation of CAMK2D. Mostly expressed in the heart and muscle of type II diabetic humans. Also found in the skeletal muscle, lung and adipose tissue. Lesser amounts in placenta and kidney.

NCBI Accession: NP_004156

UniProt: P55042