MOB1A antibody
Quick Overview for MOB1A antibody (ABIN7243568)
Target
See all MOB1A (MOBKL1B) AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Characteristics
- Polyclonal Antibody
-
Purification
- Affinity purification
-
Immunogen
- Synthetic peptide of human MOB1A
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:500-1:2000, IHC 1:50-1:200
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.4 mg/mL
-
Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
-
Alternative Name
- MOB1A
-
Background
- MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. ItsDrosophilaand mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development . There are two MOB1 proteins in humans, MOB1α and MOB1β, that are encoded by two different genes but which have greater than 95 % amino acid sequence identity.
-
Molecular Weight
- 25 kDa
-
NCBI Accession
- NP_060691
-
UniProt
- Q9H8S9
Target
-