TM7SF2 antibody

Catalog No. ABIN7243931

The Rabbit Polyclonal anti-TM7SF2 antibody is suitable to detect TM7SF2 in samples from Mouse and Human. It has been validated for WB, ELISA and IHC.

Quick Overview for TM7SF2 antibody (ABIN7243931)

Target: TM7SF2 (Transmembrane 7 Superfamily Member 2 (TM7SF2))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TM7SF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TM7SF2 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Synthetic peptide of human TM7SF2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:25-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TM7SF2

Target: TM7SF2 (Transmembrane 7 Superfamily Member 2 (TM7SF2))

Alternative Name: TM7SF2

Background: Transmembrane 7 superfamily member 2 (TM7SF2, Sterol C14-reductase, 3beta-hydroxysterol Delta-reductase) is a 418 amino acid gene product that belongs to the ERG4/ERG24 family. TM7SF2 is a seven pass transmembrane protein that can localize to the membrane of the endoplasmic reticulum. TM7SF2 is involved in the conversion of lanosterol to cholesterol and, specifically, catalyzes the NADPH dependant reduction of 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol to 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol and NADP+.

Molecular Weight: 46 kDa

NCBI Accession: NP_003264

UniProt: O76062