ECE2 antibody

Catalog No. ABIN7243970

Product Details anti-ECE2 Antibody

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Fusion protein of human ECE2

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, IHC 1:30-150, ELISA 1:2000-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Alternative Name: ECE2 (ECE2 Products)

Background: This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.

Molecular Weight: 100 kDa

UniProt: O60344

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling