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ECE2 antibody (AA 551-579)

ECE2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB43866 unconjugated
Catalog No. ABIN1881279
  • Target See all ECE2 Antibodies
    ECE2 (Endothelin Converting Enzyme 2 (ECE2))
    Binding Specificity
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-579
    Reactivity
    • 24
    • 21
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 23
    • 2
    Rabbit
    Clonality
    • 25
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ECE2 antibody is un-conjugated
    Application
    • 24
    • 14
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This ECE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the Central region of human ECE2.
    Clone
    RB43866
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:1000. IHC-P: 1:25
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Expiry Date
    6 months
  • Muzny, Scherer, Kaul, Wang, Yu, Sudbrak, Buhay, Chen, Cree, Ding, Dugan-Rocha, Gill, Gunaratne, Harris, Hawes, Hernandez, Hodgson, Hume, Jackson, Khan, Kovar-Smith, Lewis, Lozado, Metzker et al.: "The DNA sequence, annotation and analysis of human chromosome 3. ..." in: Nature, Vol. 440, Issue 7088, pp. 1194-8, (2006) (PubMed).

    Lorenzo, Khan, Wang, Tai, Chan, Cheung, Marsden: "Human endothelin converting enzyme-2 (ECE2): characterization of mRNA species and chromosomal localization." in: Biochimica et biophysica acta, Vol. 1522, Issue 1, pp. 46-52, (2001) (PubMed).

    Nagase, Ishikawa, Miyajima, Tanaka, Kotani, Nomura, Ohara: "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro." in: DNA research : an international journal for rapid publication of reports on genes and genomes, Vol. 5, Issue 1, pp. 31-9, (1998) (PubMed).

  • Target
    ECE2 (Endothelin Converting Enzyme 2 (ECE2))
    Alternative Name
    ECE2 (ECE2 Products)
    Synonyms
    ECE2 antibody, 1810009K13Rik antibody, 6330509A19Rik antibody, 9630025D12Rik antibody, BB127715 antibody, endothelin converting enzyme 2 antibody, endothelin-converting enzyme 2 antibody, ECE2 antibody, LOC702851 antibody, ece2 antibody, LOC100543478 antibody, Ece2 antibody
    Background
    Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
    NCBI Accession
    NP_001032401, NP_001093590, NP_001093591, NP_055508, NP_115707
    UniProt
    O60344
    Pathways
    Regulation of G-Protein Coupled Receptor Protein Signaling
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