TTI1 antibody
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- Target See all TTI1 Antibodies
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTI1 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthetic peptide of human TTI1
- Isotype
- IgG
- Top Product
- Discover our top product TTI1 Primary Antibody
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anti-TELO2 Interacting Protein 1 (TTI1) (AA 692-858) antibody
TTI1 Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-TELO2 Interacting Protein 1 (TTI1) (AA 41-69), (N-Term) antibodyTTI1 Reactivity: Human WB Host: Rabbit Polyclonal RB26062 unconjugated
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- Application Notes
- IHC 1:30-150, ELISA 1:2000-10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.2 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- TTI1 (TELO2 Interacting Protein 1 (TTI1))
- Alternative Name
- TTI1 (TTI1 Products)
- Background
- Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
- NCBI Accession
- NP_055472
- UniProt
- O43156
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