UCN3 antibody

Catalog No. ABIN7244717

This anti-UCN3 antibody is a Rabbit Polyclonal antibody detecting UCN3 in IHC and ELISA. Suitable for Human.

Quick Overview for UCN3 antibody (ABIN7244717)

Target: UCN3 (Urocortin 3 (UCN3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCN3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-UCN3 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human UCN3

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.4 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UCN3

Target: UCN3 (Urocortin 3 (UCN3))

Alternative Name: UCN3

Background: This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite.

UniProt: Q969E3

Pathways: Positive Regulation of Peptide Hormone Secretion