The Rabbit Polyclonal anti-Syndetin/VPS50 antibody has been validated for ELISA and IHC. It is suitable to detect Syndetin/VPS50 in samples from Human, Rat and Mouse.
Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane. Within the EARP complex, required to tether the complex to recycling endosomes. Not involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN).