CHP antibody

Catalog No. ABIN7245107

This Rabbit Polyclonal antibody specifically detects CHP in ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CHP antibody (ABIN7245107)

Target: CHP (Calcium Binding Protein P22 (CHP))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHP antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CHP Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Synthetic peptide of human CHP1

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.66 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHP

Target: CHP (Calcium Binding Protein P22 (CHP))

Alternative Name: CHP1

Background: This gene encodes a phosphoprotein that binds to the Na+/H+ exchanger NHE1. This protein serves as an essential cofactor which supports the physiological activity of NHE family members and may play a role in the mitogenic regulation of NHE1. The protein shares similarity with calcineurin B and calmodulin and it is also known to be an endogenous inhibitor of calcineurin activity.CHP1 (Calcineurin Like EF-Hand Protein 1) is a Protein Coding gene. Among its related pathways are Role of Calcineurin-dependent NFAT signaling in lymphocytes and Calcineurin-regulated NFAT-dependent transcription in lymphocytes. GO annotations related to this gene include calcium ion binding and microtubule binding. An important paralog of this gene is CHP2.

UniProt: Q99653

Pathways: Proton Transport, Regulation of Carbohydrate Metabolic Process, VEGF Signaling