HES7
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
IHC 1:30-1:150, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.72 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
HES7
(Hairy and Enhancer of Split 7 (HES7))
Alternative Name
HES7
Background
This gene encodes a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene.