CBX5 antibody
Quick Overview for CBX5 antibody (ABIN7245548)
Target
See all CBX5 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human CBX5
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Isotype
- IgG
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Application Notes
- WB 1:1000-1:5000, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.32 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBX5 (Chromobox Homolog 5 (CBX5))
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Alternative Name
- CBX5
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Background
- This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 22 kDa
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UniProt
- P45973
Target
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