RASA1 antibody
Quick Overview for RASA1 antibody (ABIN7245677)
Target
See all RASA1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Characteristics
- Polyclonal Antibody
-
Purification
- Antigen affinity purification
-
Immunogen
- Fusion protein of human RASA1
-
Isotype
- IgG
-
-
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibody
RASA1 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2C12 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1047) antibodyRASA1 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1E6 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 403-596) antibodyRASA1 Reactivity: Human WB, ELISA, IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 201-500) antibodyRASA1 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (C-Term) antibodyRASA1 Reactivity: Human, Rat, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 Reactivity: Human WB Host: Mouse Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 966-993), (C-Term) antibodyRASA1 Reactivity: Human WB Host: Rabbit Polyclonal RB31772 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 1-870) antibodyRASA1 Reactivity: Human IP Host: Rabbit Polyclonal unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 948-1048) antibodyRASA1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2C12 unconjugated
anti-RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) (AA 953-1002) antibodyRASA1 Reactivity: Human, Rat, Mouse, Dog, Chicken, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Bat, Pig WB Host: Rabbit Polyclonal unconjugated
-
-
Application Notes
- IHC 1:30-1:150, ELISA 1:5000-1:10000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- RASA1 (RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1))
-
Alternative Name
- RASA1
-
Background
- The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.
-
UniProt
- P20936
-
Pathways
- Regulation of Actin Filament Polymerization, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals
Target
-
