SPCS2 antibody

Catalog No. ABIN7245812

This Rabbit Polyclonal antibody specifically detects SPCS2 in ELISA, WB and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SPCS2 antibody (ABIN7245812)

Target: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPCS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SPCS2 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human SPCS2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPCS2

Target: SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))

Alternative Name: SPCS2

Background: SPCS2 (signal peptidase complex subunit 2), also known as SPC25 or microsomal signal peptidase 25 kDa subunit, is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 25 kDa

UniProt: Q15005

Pathways: Peptide Hormone Metabolism