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SPCS2 antibody (AA 2-100) (HRP)

SPCS2 Reactivity: Mouse WB Host: Rabbit Polyclonal HRP
Catalog No. ABIN6945026
$470.46
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all SPCS2 Antibodies
    SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    AA 2-100
    Reactivity
    • 15
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPCS2 antibody is conjugated to HRP
    Application
    • 6
    • 6
    • 2
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Human,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SPCS2
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    SPCS2 (Signal Peptidase Complex Subunit 2 Homolog (SPCS2))
    Alternative Name
    SPCS2 (SPCS2 Products)
    Synonyms
    RGD1311253 antibody, 5730406I15Rik antibody, AA408713 antibody, mKIAA0102 antibody, SPC25 antibody, signal peptidase complex subunit 2 antibody, signal peptidase complex subunit 2 homolog (S. cerevisiae) antibody, Spcs2 antibody, SPCS2 antibody
    Background

    SPCS2 is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

    Subcellular location: Cell membrane

    Synonyms: Microsomal signal peptidase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae), SPase 25 kDa subunit, SPCS2, SPCS2_HUMAN.

    Gene ID
    9789
    UniProt
    Q15005
    Pathways
    Peptide Hormone Metabolism
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