BHMT2 antibody

Catalog No. ABIN7246028

This anti-BHMT2 antibody is a Rabbit Polyclonal antibody detecting BHMT2 in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for BHMT2 antibody (ABIN7246028)

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BHMT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-BHMT2 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human BHMT2

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.78 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BHMT2

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Alternative Name: BHMT2

Background: Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. The protein encoded by this gene is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Anomalies in homocysteine metabolism have been implicated in disorders ranging from vascular disease to neural tube birth defects such as spina bifida. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 40 kDa

UniProt: Q9H2M3

Pathways: Methionine Biosynthetic Process