C1ORF106 antibody

Catalog No. ABIN7246082

This anti-C1ORF106 antibody is a Rabbit Polyclonal antibody detecting C1ORF106 in ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for C1ORF106 antibody (ABIN7246082)

Target: C1ORF106 (Chromosome 1 Open Reading Frame 106 (C1ORF106))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1ORF106 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-C1ORF106 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human C1orf106

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for C1ORF106

Target: C1ORF106 (Chromosome 1 Open Reading Frame 106 (C1ORF106))

Alternative Name: C1orf106

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf106 gene product has been provisionally designated C1orf106 pending further characterization.

UniProt: Q3KP66