CCDC112 antibody

Catalog No. ABIN7246133

This anti-CCDC112 antibody is a Rabbit Polyclonal antibody detecting CCDC112 in ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for CCDC112 antibody (ABIN7246133)

Target: CCDC112 (Coiled-Coil Domain Containing 112 (CCDC112))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC112 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CCDC112 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human CCDC112

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCDC112

Target: CCDC112 (Coiled-Coil Domain Containing 112 (CCDC112))

Alternative Name: CCDC112

Background: CCDC112 (coiled-coil domain containing 112), also known as MBC1 (mutated in bladder cancer 1), is a 446 amino acid protein. The gene encoding CCDC112 is located on chromosome 5. Due to alternative splicing events, CCDC112 exists as two isoforms. Chromosome 5 comprises about 6 % of human genomic DNA and contains 181 million base pairs encoding around 1,000 genes. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

UniProt: Q8NEF3