GARS antibody
Quick Overview for GARS antibody (ABIN7246172)
Target
See all GARS AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Fusion protein of human GARS
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- GARS (Glycyl-tRNA Synthetase (GARS))
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Alternative Name
- GARS
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Background
- This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 83 kDa
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UniProt
- P41250
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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