p63 antibody

Catalog No. ABIN7246340

This anti-p63 antibody is a Rabbit Polyclonal antibody detecting p63 in ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for p63 antibody (ABIN7246340)

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p63 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-p63 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human TP63

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.14 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for p63

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Alternative Name: TP63

Background: TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.

UniProt: Q9H3D4