MANSC1 antibody

Catalog No. ABIN7247171

Product Details anti-MANSC1 Antibody

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MANSC1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human MANSC1

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MANSC1

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Alternative Name: MANSC1 (MANSC1 Products)

Synonyms: MANSC1 antibody, DKFZp469A172 antibody, 9130403P13Rik antibody, LOH12CR3 antibody, MANSC domain containing 1 antibody, MANSC1 antibody, Mansc1 antibody, LOC777123 antibody

Background: MANSC1 (MANSC domain-containing protein 1), also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

UniProt: Q9H8J5