KIAA0101 antibody

Catalog No. ABIN7247369

This Rabbit Polyclonal antibody specifically detects KIAA0101 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for KIAA0101 antibody (ABIN7247369)

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIAA0101 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-KIAA0101 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PCLAF

Isotype: IgG

Application Details

Application Notes: IHC 1:40-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.84 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KIAA0101

Target: KIAA0101 (PAF) (PCNA Clamp Associated Factor (PAF))

Alternative Name: PCLAF

Background: PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.

UniProt: Q15004

Pathways: Chromatin Binding