PAFAH1B3 antibody

Catalog No. ABIN7247612

This Rabbit Polyclonal antibody specifically detects PAFAH1B3 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PAFAH1B3 antibody (ABIN7247612)

Target: PAFAH1B3 (Platelet-Activating Factor Acetylhydrolase 1b, Catalytic Subunit 3 (29kDa) (PAFAH1B3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAFAH1B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-PAFAH1B3 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PAFAH1B3

Isotype: IgG

Application Details

Application Notes: WB 1:1000-1:5000, IHC 1:50-1:200, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PAFAH1B3

Target: PAFAH1B3 (Platelet-Activating Factor Acetylhydrolase 1b, Catalytic Subunit 3 (29kDa) (PAFAH1B3))

Alternative Name: PAFAH1B3

Background: This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 26 kDa

UniProt: Q15102