PPM1M antibody

Catalog No. ABIN7247633

The Rabbit Polyclonal anti-PPM1M antibody is suitable to detect PPM1M in samples from Human and Mouse. It has been validated for ELISA and IHC.

Quick Overview for PPM1M antibody (ABIN7247633)

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1M antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-PPM1M Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human PPM1M

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.74 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PPM1M

Target: PPM1M (Protein Phosphatase 1M (PP2C Domain Containing) (PPM1M))

Alternative Name: PPM1M

Background: PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

UniProt: Q96MI6