Cyclin T2 antibody
Quick Overview for Cyclin T2 antibody (ABIN7004649)
Target
See all Cyclin T2 (CCNT2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human CCNT2
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.8 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cyclin T2 (CCNT2)
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Alternative Name
- CCNT2
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Background
- The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 81 kDa
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UniProt
- O60583
Target
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