The Rabbit Polyclonal anti-ABHD2 antibody (ABIN7248077) specifically detects ABHD2 in ELISA and IHC.
The antibody is reactive with Human and Mouse samples.
ABHD2
Reactivity: Human
Host: Rabbit
Polyclonal
FITC
Application Notes
IHC 1:40-1:200, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
1.14 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
ABHD2
(Abhydrolase Domain Containing 2 (ABHD2))
Alternative Name
ABHD2
Background
ABHD2 encodes a protein containing an alpha/beta hydrolase fold, which is a catalytic domain found in a wide range of enzymes. The encoded protein is an acylglycerol lipase that catalyzes the hydrolysis of endocannabinoid arachidonoylglycerol from the cell membrane. This leads to activation of the sperm calcium channel CatSper, which results in sperm activation. Alternative splicing of this gene results in two transcript variants encoding the same protein.ABHD2 (Abhydrolase Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include carboxylic ester hydrolase activity. An important paralog of this gene is ABHD3.