ABCD1
Reactivity: Human, Mouse, Rat
IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC 1:60-1:450, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
1.5 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
ABCD1
(ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))
Alternative Name
ABCD1
Background
ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.