ZNF828 antibody
Quick Overview for ZNF828 antibody (ABIN7248329)
Target
See all ZNF828 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human CHAMP1
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Isotype
- IgG
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anti-Zinc Finger Protein 828 (ZNF828) (AA 563-812) antibody
ZNF828 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (AA 261-310) antibodyZNF828 Reactivity: Human, Mouse, Horse WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (AA 1-812) antibodyZNF828 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (AA 203-229) antibodyZNF828 Reactivity: Human WB Host: Rabbit Polyclonal RB37490 unconjugated
anti-Zinc Finger Protein 828 (ZNF828) (Middle Region) antibodyZNF828 Reactivity: Human, Mouse, Rat, Horse, Dog, Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
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Application Notes
- IHC 1:30-1:150, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.6 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- ZNF828 (Zinc Finger Protein 828 (ZNF828))
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Alternative Name
- CHAMP1
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Background
- CHAMP1 (chromosome alignment maintaining phosphoprotein 1), also known as ZNF828 or C13orf8, is a 812 amino acid protein containing one C2H2-type zinc finger. CHAMP1 is required for the proper alignment of chromosomes during metaphase, undergoing CDK1-dependent phosphorylation at multiple sites during mitosis. The phosphorylation counteracts the negative chromosomal alignment regulation of the zinc-finger domain of CHAMP1. One region of CHAMP1, the FPE region, is responsible for spindle and kinetochore localization, which is essential for proper chromosome alignment. CHAMP1 interacts with MAD2L2, PGOZ, CBX1, CBX3 and CBX5, and may recruit CENPE and CENPF to the kinetochore. The CHAMP1 gene is located on chromosome 13 and is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat and chicken.
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UniProt
- Q96JM3
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Pathways
- Maintenance of Protein Location
Target
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