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PIWIL2 antibody

PIWIL2 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7004802
  • Target See all PIWIL2 Antibodies
    PIWIL2 (Piwi-Like 2 (PIWIL2))
    Reactivity
    • 30
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 31
    • 3
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PIWIL2 antibody is un-conjugated
    Application
    • 26
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    Characteristics
    Polyclonal Antibody
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human PIWIL2
    Isotype
    IgG
    Top Product
    Discover our top product PIWIL2 Primary Antibody
  • Application Notes
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.7 mg/mL
    Buffer
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PIWIL2 (Piwi-Like 2 (PIWIL2))
    Alternative Name
    PIWIL2 (PIWIL2 Products)
    Synonyms
    si:dkey-88f5.1 antibody, zili antibody, Piwil1l antibody, mili antibody, CT80 antibody, HILI antibody, PIWIL1L antibody, piwil2 antibody, piwi like RNA-mediated gene silencing 2 antibody, piwi-like RNA-mediated gene silencing 2 antibody, piwil2 antibody, Piwil2 antibody, PIWIL2 antibody
    Background
    PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells. Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Plays an essential role in meiotic differentiation of spermatocytes, germ cell differentiation and in self-renewal of spermatogonial stem cells. Its presence in oocytes suggests that it may participate in similar functions during oogenesis in females. Indirectly modulate expression of genes such as PDGFRB, SLC2A1, ITGA6, GJA7, THY1, CD9 and STRA8. Inhibits tumor cell growth when repressed. When overexpressed, acts as an oncogene by inhibition of apoptosis and promotion of proliferation in tumors
    UniProt
    Q8TC59
    Pathways
    Stem Cell Maintenance
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