HIST1H2BA antibody
Quick Overview for HIST1H2BA antibody (ABIN7248536)
Target
Reactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Synthetic peptide of human HIST1H2BA
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Isotype
- IgG
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anti-Histone Cluster 1, H2ba (HIST1H2BA) (acLys126) antibody
HIST1H2BA Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Histone Cluster 1, H2ba (HIST1H2BA) (AA 1-30), (N-Term) antibodyHIST1H2BA Reactivity: Human WB Host: Rabbit Polyclonal RB38815 unconjugated
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Application Notes
- WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.98 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- HIST1H2BA (Histone Cluster 1, H2ba (HIST1H2BA))
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Alternative Name
- HIST1H2BA
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Background
- The nucleosome, made up of four core histone proteins (H2A, H2B, H3, and H4), is the primary building block of chromatin. Originally thought to function as a static scaffold for DNA packaging, histones have now been shown to be dynamic proteins, undergoing multiple types of post-translational modifications, including acetylation, phosphorylation, methylation, and ubiquitination , acetylation of specific lysine residues creates docking sites that facilitate recruitment of many transcription and chromatin regulatory proteins that contain a bromodomain, which binds to acetylated lysine residues . Histone H2B is rapidly phosphorylated at irradiation-induced DNA damage foci in mouse embryonic fibroblasts .
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 14 kDa
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UniProt
- Q96A08
Target
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