FBXL4
Reactivity: Human, Rat
WB, IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 750
Application Notes
IHC 1:30-1:150, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.66 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
FBXL4
(F-Box and Leucine-Rich Repeat Protein 4 (FBXL4))
Alternative Name
FBXL4
Background
This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants.