Mtfp1
Reactivity: Rat
IF (cc), IF (p)
Host: Rabbit
Polyclonal
AbBy Fluor® 647
Application Notes
WB 1:500-1:2000, IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
Mtfp1
(Mitochondrial Fission Process 1 (Mtfp1))
Alternative Name
MTFP1
Background
MTP18 (mitochondrial 18 kDa protein), also known as HSPC242, is a 166 amino acid protein essential for cell viability. MTP18 may also have a role in maintaining the integrity of the mitochondrial network. Localized to the mitochonrion, expression of MTP18 is regulated by the PI 3-kinase pathway. Loss of function of MTP18 results in the release of cytochrome c, which subsequently activates the caspase cascade and leads to apoptosis.