ZWILCH antibody
Quick Overview for ZWILCH antibody (ABIN7249262)
Target
See all ZWILCH AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Characteristics
- Polyclonal Antibody
-
Purification
- Antigen affinity purification
-
Immunogen
- Synthetic peptide of human ZWILCH
-
Isotype
- IgG
-
-
-
-
Application Notes
- WB 1:1000-1:5000, ELISA 1:2000-1:10000
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.6 mg/mL
-
Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
-
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ZWILCH (Zwilch, Kinetochore Associated, Homolog (ZWILCH))
-
Alternative Name
- ZWILCH
-
Background
- This protein is essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. And it is required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. ZWILCH gene is deleted in a patient suffering from colorectal cancer with chromosomal instability.
-
Molecular Weight
-
Observed_MW: Refer to figures
Calculated_MW: 67 kDa
-
UniProt
- Q9H900
Target
-