N-Cadherin antibody
Quick Overview for N-Cadherin antibody (ABIN7249458)
Target
See all N-Cadherin (CDH2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin
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Isotype
- IgG
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Application Notes
- WB 1:500-1:2000, IHC 1:300-1:800
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 200 μg/mL
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Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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Alternative Name
- N-cadherin
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Background
- Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity .
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Molecular Weight
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Observed_MW: 120 kDa
Calculated_MW: 100/120/140 kDa
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UniProt
- P19022, P15116, Q9Z1Y3
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Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
Target
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