NOS1 antibody
-
- Target See all NOS1 Antibodies
- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
-
Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This NOS1 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse nNOS
- Isotype
- IgG
- Top Product
- Discover our top product NOS1 Primary Antibody
-
-
- Application Notes
- WB 1:500-1:2000, IHC 1:300-1:800
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 350 μg/mL
- Buffer
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- NOS1 (Nitric Oxide Synthase 1, Neuronal (NOS1))
- Alternative Name
- NOS1 (NOS1 Products)
- Background
- The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.
- Molecular Weight
-
Observed_MW: 161 kDa
Calculated_MW: 161 kDa
- UniProt
- P29475, P29476, Q9Z0J4
- Pathways
- Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction
-