MBP antibody

Catalog No. ABIN7249818

This anti-MBP antibody is a Rabbit Polyclonal antibody detecting MBP in WB and IHC. Suitable for Rat and Mouse.

Quick Overview for MBP antibody (ABIN7249818)

Target: MBP

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-MBP Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse Myelin Basic Protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:200-1:600

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 300 μg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MBP

Target: MBP

Background: MBP belongs to the myelin basic protein family. The classic group of MBP isoforms (isoform 4-isoform 14) are the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. MBP has six isoforms. Catalog#10458-1-AP is capable of recognizing multiple isoforms of MBP.

Molecular Weight:

Observed_MW: 17-22 kDa

Calculated_MW: 17-22 kDa

UniProt: P04370, P02688