CD16 antibody

Catalog No. ABIN7250149

This Mouse Monoclonal antibody specifically detects CD16 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD16 antibody (ABIN7250149)

Target: CD16

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 2B1

Product Details anti-CD16 Antibody

Characteristics: Monoclonal Antibody

Purification: Protein A purification

Immunogen: Synthetic Peptide

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD16

Target: CD16

Alternative Name: CD16

Background: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage.

Molecular Weight:

Observed_MW: 45 kDa

Calculated_MW: 28 kDa

UniProt: P08637, O75015

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process