HDAC6 antibody (pSer22)
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- Target See all HDAC6 Antibodies
- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Binding Specificity
- pSer22
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
- Isotype
- IgG
- Top Product
- Discover our top product HDAC6 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HDAC6 (Histone Deacetylase 6 (HDAC6))
- Alternative Name
- HDAC6 (HDAC6 Products)
- Background
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
- Molecular Weight
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Observed_MW: 131 kDa
Calculated_MW: 131 kDa
- UniProt
- Q9UBN7
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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