HDAC2 antibody
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- Target See all HDAC2 Antibodies
- HDAC2 (Histone Deacetylase 2 (HDAC2))
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Reactivity
- Human, Mouse, Rat, Monkey
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Characteristics
- Polyclonal Antibody
- Purification
- Affinity purification
- Immunogen
- Synthesized peptide derived from human HDAC2 around the non-phosphorylation site of Ser394.
- Isotype
- IgG
- Top Product
- Discover our top product HDAC2 Primary Antibody
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- Application Notes
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- HDAC2 (Histone Deacetylase 2 (HDAC2))
- Alternative Name
- HDAC2 (HDAC2 Products)
- Background
- Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity.
- Molecular Weight
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Observed_MW: 55 kDa
Calculated_MW: 55 kDa
- UniProt
- Q92769
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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