ABI2 antibody

Catalog No. ABIN7251859

The Rabbit Polyclonal anti-ABI2 antibody has been validated for WB and ELISA. It is suitable to detect ABI2 in samples from Human and Mouse.

Quick Overview for ABI2 antibody (ABIN7251859)

Target: ABI2 (Abl-Interactor 2 (ABI2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ABI2 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ABI2

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.96 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ABI2

Target: ABI2 (Abl-Interactor 2 (ABI2))

Alternative Name: ABI2

Background: May act in regulation of cell growth and transformation by interacting with nonreceptor tyrosine kinases ABL1 and/or ABL2. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Regulates ABL1/c-Abl-mediated phosphorylation of MENA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.

Molecular Weight:

Observed_MW: Refer to figures

Calculated_MW: 56 kDa

UniProt: Q9NYB9