NDUFB11 antibody
Quick Overview for NDUFB11 antibody (ABIN7252021)
Target
See all NDUFB11 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Characteristics
- Polyclonal Antibody
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Purification
- Antigen affinity purification
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Immunogen
- Full length fusion protein
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Isotype
- IgG
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Application Notes
- WB 1:1000-1:5000, IHC 1:50-1:300, ELISA 1:5000-1:10000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.6 mg/mL
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Buffer
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- NDUFB11 (NADH Dehydrogenase (Ubiquinone) 1 beta Subcomplex, 11, 17.3kDa (NDUFB11))
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Alternative Name
- NDUFB11
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Background
- Complex 1 (also known as NADH dehydrogenase) of the electron transport chain (respiratory chain) is an enzymatic complex that catalyzes the transfer of electrons from NADH to ubiquinone. Free energy from the reaction is conserved in the transfer of protons into the intermembrane space to create an electrochemical proton gradient, a driving force for ATP synthesis. Complex 1 is a complicated, multi-protein, L-shaped complex composed of at least 45 different subunits and located in the mitochondrial inner membrane. NDUFB11 (NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11), also known as ESSS, Np15, Np17.3 (neuronal protein 17.3) or p17.3, is a hydrophobic transmembrane protein belonging to the Complex I NDUFB11 subunit family. Ubiquitously expressed, NDUFB11 localizes to the inner membrane of the mitochondrion and functions as an accessory subunit of Complex I. The cAMP-dependent phosphorylation of NDUFB11 is important for the regulation of Complex I activity.
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Molecular Weight
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Observed_MW: Refer to figures
Calculated_MW: 17 kDa
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UniProt
- Q9NX14
Target
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