UBA7 antibody

Catalog No. ABIN7252213

This Rabbit Polyclonal antibody specifically detects UBA7 in ELISA and IHC. It exhibits reactivity toward Human.

Quick Overview for UBA7 antibody (ABIN7252213)

Target: UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBA7 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-UBA7 Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human UBA7

Isotype: IgG

Application Details

Application Notes: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.6 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for UBA7

Target: UBA7 (Ubiquitin-Like Modifier Activating Enzyme 7 (UBA7))

Alternative Name: UBA7

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein.

UniProt: P41226