ZC3H7A antibody

Catalog No. ABIN7252777

This anti-ZC3H7A antibody is a Rabbit Polyclonal antibody detecting ZC3H7A in ELISA and IHC. Suitable for Human.

Quick Overview for ZC3H7A antibody (ABIN7252777)

Target: ZC3H7A (Zinc Finger CCCH-Type Containing 7A (ZC3H7A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZC3H7A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-ZC3H7A Antibody

Characteristics: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogen: Fusion protein of human ZC3H7A

Isotype: IgG

Application Details

Application Notes: IHC 1:50-1:300, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.9 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZC3H7A

Target: ZC3H7A (Zinc Finger CCCH-Type Containing 7A (ZC3H7A))

Alternative Name: ZC3H7A

Background: The zinc finger CCCH domain-containing protein 7A (ZC3H7A), also known as ZC3H7, HSPC055 or ZC3HDC7, is a 971 amino acid protein that contains a C3H1-type zinc finger domain, three C3H1-type zinc fingers and three TPR repeats. Belonging to the ZC3H12 family, ZC3H7A localizes to the nucleus. Existing as two alternatively spliced isoforms, ZC3H7A is encoded by a gene located on human chromosome 16p13.13. Chromosome 16 makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene.

UniProt: Q8IWR0

Pathways: SARS-CoV-2 Protein Interactome