H3F3B
Reactivity: Human, Mouse, Rat
ELISA, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
IHC 1:30-1:150, ELISA 1:5000-1:10000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.72 mg/mL
Buffer
PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target
H3F3B
(H3 Histone, Family 3B (H3.3B) (H3F3B))
Alternative Name
H3F3B
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.